Apresentamos, abaixo, a produção científica, patentes e impactos da pesquisa em andamento.


COMUNICAÇÕES NACIONAIS

M.C. Artal, F. Kummrow, R.D. Holtz, O.L. Alves and G.A. Umbuzeiro
The role of silver and vanadium to the toxicity of silver vanadate nanowires decorated with silver nanoparticles
ECOTOX 2012
Porto de Galinhas - PE (2012)

D.T. Castro, R.D. Holtz, O.L. Alves, C.H. Silva-Lovato, E. Watanabe e A.C. Reis
Efeito da incorporação de um nanocomposto de prata na atividade antimicrobiana de resina acrílica odontológica
SBPqO - 30a Reunião Anual da Sociedade Brasileira de Pesquisa em Odontologia Águas de Lindóia - SP (2013)

L.G.S. Mariotto, D.T. Castro, M.L.C. Valente, C.H. Silva-Lovato CH, O.L. Alves e A.C. Reis
Atividade antifúngica e resistência à compressão de uma resina acrílica contendo vanadato de prata nanoestruturado
SBPqO - 31a Reunião Anual da Sociedade Brasileira de Pesquisa em Odontologia
Águas de Lindóia - SP (2014)

D.T. Castro, M.L.C. Valente, C.P. Aires, O.L. Alves e A.C. Reis
Liberação elementar de íons e citotoxicidade de nanocompostos antimicrobianos para aplicação protética
SBPO - Reunião Anual da Sociedade Brasileira de Pesquisa Odontológica
Campinas - SP (2016)

G.H. Da Silva, J.R. Lopes, L.S. Bortolozzo, F. Coa, R.T.R. Monteiro, O.L. Alves, and D.S.T. Martinez
Toxicity evaluation of gelatin-silver nanoparticles to microorganisms and fish embryos
SBPMAT - Congresso Brasileiro da Sociedade Brasileira de Pesquisa em Materiais
Campinas - SP (2016)


COMUNICAÇÕES INTERNACIONAIS

N. Duran, P.D. Marcato, R. de Conti, O.L. Alves and M. Brocchi
Silver nanoparticles: control of pathogens, toxicity and cytotoxicity
International Conference on Nanomaterial Toxicology - ICONTOX
Lucknow, India (2008)

R.D. Holtz, O.L. Alves, D. Martins, M. Brocchi and N. Durán
Development of nanostructured silver vanadates with potential antibacterial activity
4th International Symposium on Advanced Materials and Nanostructures
Santo André, São Paulo, Brasil (2009)

R.D. Holtz, A.G. Souza Filho, B. Lima, M. Brocchi and O.L. Alves
A facile route for synthesizing silver vanadate nanowires decorated with silver nanoparticles
E-MRS 2010 - European Materials Research Society Spring Meeting 2010
Strasbourg, França (2010)

B.A. Lima, R.D. Holtz, N. Durán, O.L. Alves and M. Brocchi
Synergistic effect on antibacterial activity of violacein by addition of nanostructured silver vanadate
ICAR - International Conference on Antimicrobial Research
Valladolid, Espanha (2010)

M.C. Artal, R.D. Holtz, A.Caloto-Oliveira, G.De-Almeida, O.L. Alves and G.A. Umbuzeiro
Understanding the toxicity of silver vanadates nanowires decorated with silver nanoparticles
International Symposium on Toxicity Assessment (ISTA 15), Session: Environmental Safety and Public Health (Oral Presentation)
Hong Kong, China (2011)

R.D. Holtz, B. Lima, A.G.Souza Filho, M.Brocchi and O.L. Alves
Nanostructured silver vanadates: a promissing antibacterial additive to water based paints
5th International Meeting on Developments in Materials, Processes and Applications of Emerging Technologies (Oral Presentation)
Alvor, Portugal (2011)

P.D. Marcato, N.V. Parizatto, D. Stefani and O.L. Alves
New antimicrobial hybrid material based on biosynthetic silver nanoparticles
5th International Meeting on Developments in Materials, Processes and Applications of Emerging Technologies (MPA - 195)
Alvor, Portugal (2011)

P.D. Marcato, S.C. Huber, G. Nakasato, M. Brocchi, I.R. Ferreira, P.S. Melo, O.L Alves and N. Duran.
Production of antibacterial textile fabrics with biogenic silver nanoparticles; antibacterial activity and cytotoxicity
5th International Meeting on Developments in Materials, Processes and Applications of Emerging Technologies (MPA - 196)
Alvor, Portugal (2011)

R.D. Holtz, B.A. Lima, A.G. Souza Filho, M. Brocchi and O.L. Alves
Development of a novel nanostructured antibacterial additive based on silver and vanadium and its potential applications
ICAR - II International Conference on Antimicrobial Research
Lisbon, Portugal (2012)

G.A. Umbuzeiro, M.C. Artal, F. Kummrow, R.D. Holtz and O.L. Alves
The role of silver and vanadium to the ecotoxicity of silver vanadate nanowires decorated with silver nanoparticles
NANOSAFE 2012 - International Conference on Safe production and use of nanomaterials
Grenoble, France (2012)

R.D. Holtz, B.A. Lima, M. Brocchi and O.L. Alves
The promissing use of nanostructured silver vanadates as antibacterial additive to coatings used in places with risks of bacterial contamination
9th International Vanadium Symposium
Padova, Italy (2014)


TRABALHOS PUBLICADOS EM PERIÓDICOS

N.E.D. Caballero, P.D. Marcato, O.L. Alves, G.I.H. de Souza and E. Esposito
Mechanistic aspects of biosynthesis of silver nanoparticles by several fusarium oxysporum strains
Journal of Nanobiotechnology, Vol. 3, n. 8 (2005)

N.E.D. Caballero, P.D. Marcato, G.I.H. de Souza, O.L. Alves and E. Esposito
Antibacterial effect of silver nanoparticles produced by fungal process on textil fabrics and their effluent treatment
Journal of Biomedical Nanotechnology, Vol. 3 (2), 203-208 (2007)
http://www.lqes.iqm.unicamp.br/images/publicacoes_teses_trabalhosrev_2007_antibacterial.pdf

N. Durán, P.D. Marcato, R. De Conti, O.L. Alves, F.T.M. Costa and M. Brocchi
Potential use of silver nanoparticles on pathogenic bacteria, their toxicity and possible mechanisms of action
Journal of Brazilian Chemical Society, Vol. 21 (6), 949-959 (2010)
DOI 10.1590/S0103-50532010000600002

R.D. Holtz, A.G. Souza Filho, M. Brocchi, D. Martins, N. Durán and O.L. Alves
Development of nanostructured silver vanadates decorated with silver nanoparticles asa novel antibacterial agent
Nanotechnology, Vol. 21 (18) (2010)
DOI 10.1088/0957-4484/21/18/185102

N. Durán, P.D. Marcato, O.L. Alves, João P.S. da Silva, G.I.H. de Souza, F.A. Rodrigue and E. Esposito
Ecosystem protection by effluent bioremediation: silver nanoparticles impregnation in a textil fabrics process
Journal of Nanoparticle Research, Vol. 12, 285-292 (2010)
DOI 10.1007/s11051-009-9606-1

A.G. Rodrigues, L.Y. Ping, P.D. Marcato, O.L. Alves, M.C.P. Silva, R.C. Ruiz, I.S. Melo, L.Tasic and A.O. de Souza
Biogenic antimicrobial nanoparticles produced by fungi
Applied Microbiology and Biotechnology, Vol. 95, 1-8 (2012)
DOI: 10.1007/s00253-012-4209-7

P.D. Marcato, G. Nakasato, M.Brocchi, P.S. Melo, S.C. Huber, I.R. Ferreira, O.L. Alves and N. Durán
Biogenic silver nanoparticles:antibacterial and cytotoxicity applied to textile fabrics
Journal of Nano Research, Vol. 20, 69-76 (2012)
DOI: 10.4028/www.scientific.net/JNanoR.20.69

P.D. Marcato, M. Durán, S.C. Huber, M. Rai, P.S. Melo, O.L. Alves and N. Durán
Biogenic silver nanoparticles and its antifungal activity as a new topical transungual drug
Journal of Nano Research, Vol. 20, 99-107 (2012)
DOI: 10.4028/www.scientific.net/JNanoR.20.99

R.D. Holtz, B.A. Lima, A.G. Souza Filho, M. Brocchi and O.L. Alves
Nanostructured silver vanadate as a promising antibacterial additive to water-based paints
Nanomedicine: Nanotechnology, Biology and Medicine, Vol. 8 (6), 935-940 (2012)
DOI: 10.1016/j.nano.2011.11.012

P.D. Marcato, N.V. Parizotto, D.S.T. Martinez, A.J. Paula, I.R. Ferreira, P.S. Melo, N. Durán, and O.L. Alves
New hybrid material based on layered double hydroxides and biogenic silver nanoparticles: antimicrobial activity and cytotoxic effect
Journal of the Brazilian Chemical Society, Vol. 24 (2), 266-272 (2013)
http://www.jbcs.sbq.org.br/imagebank/pdf/v24n2a13.

M.C. Artal, R.D. Holtz, F. Kummrow, O.L. Alves and G.A. Umbuzeiro
The role of silver and vanadium release in the toxicity of silver vanadate nanowires toward Daphnia similis
Environmental Toxicology and Chemistry, Vol. 32 (4), 908-912 (2013)
DOI: 10.1002/etc.2128

D.T. Castro, R.D. Holtz, O.L. Alves, E. Watanabe, M.L.C. Valente, C.H.L. Silva and A.C. Reis
Development of a novel resin with antimicrobial properties for dental application
Journal of Applied Oral Science, Vol. 22 (5), 442-449 (2014)
http://dx.doi.org/10.1590/1678-775720130539

P.D. Marcato, L.B. de Paula, P.S. Melo, I.R. Ferreira, A.B.A. Almeida, A.S. Torsoni and O.L. Alves
In vivo evaluation of complex biogenic silver nanoparticle and enoxaparin in wound healing
Journal of Nanomaterials, Vol. 2015, Article ID 439820 (2015)
DOI: 10.1155/2015/439820

D.T. Castro, M.L. Valente, C.L. Silva, E. Watanabe, R.L. Siqueira, M.A. Schiavon, O.L. Alves and A.C. dos Reis
Evaluation of antibiofilm and mechanical properties of new nanocomposites based onacrylic resins and silver vanadate nanoparticles
Archives of Oral Biology, Vol. 67, 46-53 (2016)
DOI: 10.1016/j.archoralbio.2016.03.002

D.T. Castro, M. Valente, J.A. Agnelli, C.L. da Silva, E. Watanabe, R. Siqueira, O.L. Alves, R.D. Holtz and A.C. dos Reis
In vitro study of the antibacterial properties and impact strength of dental acrylic resins modified with a nanomaterial
The Journal of Prosthetic Dentistry, Volume 115 (2), 238–246 (2016)
DOI: 10.1016/j.prosdent.2015.09.003

D. Ballottin, S. Fulaz, F. Cabrini, J. Tsukamoto, N. Durán, O.L. Alves and L. Tasic
Antimicrobial textiles: biogenic silver nanoparticles against Candida and Xanthomonas
Materials Science & Engineering B: Solid-State Materials for Advanced
Technology, Vol. 75, 582-589 (2017)
DOI: 10.1016/j.msec.2017.02.110

D.T. Castro, M.L. Valente, C.Aires, O.L. Alves and A.C. dos Reis
Elemental ion release and cytotoxicity of antimicrobial acrylic resins incorporated with nanomaterial
Gerodontology, 1-6 (2017)
DOI: 10.111/ger.12267

A.P.M. Monteiro, R.D. Holtz, L.C. Fonseca, C.H.Z. Martins, M. Sousa, L.A.V. Luna, D.S. Maia and O.L. Alves
Nano silver vanadate AgVO3: Synthesis, new functionalities and applications
Chemical Record (Chemical Society of Japan) (2018)
DOI: 10.1002/tcr.201700086


PATENTES DEPOSITADAS (NACIONAIS)

N.E.D. Caballero, P.D. Marcato, G.I.H. de Souza, O.L. Alves e E. Esposito
Processo de produção de nanopartículas de prata estabilizadas com proteínas na produção de tecidos antibacterianos e o tratamento dos efluentes produzidos
BR200605681; PI 0605681-4 (INPI), 18.09.2006

A.C. dos Reis, D.T. de Castro, O.L. Alves, R.D. Holtz e M.L.C. Valente
Composição antimicrobiana consistida de um material moldável e um agente antimicrobiano, e seu uso
IQ/USP
BR102014025317 , 10.10.2014

N.E.D. Caballero, P.F. Andrade e O.L. Alves
Filme nanocompósito, método de obtenção e usos
BR102015004870 (Derwent/INPI), 05.03.2015


PATENTES DEPOSITADAS (INTERNACIONAIS)

N.E.D. Caballero, P.D. Marcato, G.I.H. de Souza, O.L. Alves and E. Esposito
Method for producing nanoparticles, protein stabilized silver nanoparticles, production of antibacterial textile products, antibacterial textile products and bioremediation method
Patente de origem: BR200605681, 18.09.06
PCT/BR2007000233, 11.09.2007
WO2008034207, 27.03.08


TESES DEFENDIDAS NO LQES RELACIONADAS COM O TEMA

Desenvolvimento de nanoestruturas de vanadatos de prata, cério e bismuto e avaliação como novos agentes antibacterianos
Raphael Dias Holtz
Doutorado, Instituto de Química, UNICAMP (2012


IMPACTOS DA PESQUISA REALIZADA

NanoBioss organiza Workshop sobre nanopartículas de prata e sua ação frente a sistemas biológicos.

Brasileiros criam tecido antibacteriano.

Prata biológica.

Equipe da FORP promove inovação na odontologia com estudo de nanomateriais.

Trabalho realizado no Instituto de Química da Unicamp sobre nanopartículas de prata biogênica atinge mais de 30.000 downloads.

Nanotecnologia fecha as portas para infecção hospitalar.

Pesquisa da Unicamp cria tecido que reduz casos de infecção hospitalar.

Quadragésima primeira tese realizada no LQES.

‘Cápsula’ química retarda o envelhecimento de frutas

Nanomaterial antimicrobiano inova odontologia

Pesquisadores desenvolvem tinta de parede contra bactérias superresistentes

Tecido Antibacteriano

Nanomaterial para combater bactérias

Nanobiotecnologia verde: biossínteses de nanopartículas metálicas e suas aplicações como nanoantimicrobianos

Prata biológica: Nanopartículas feitas a partir de fungos são testadas com sucesso em tecidos antibacterianos e em ferimentos


OFERTA DE TECNOLOGIA

Agência de Inovação da Unicamp - INOVA, http://www.inova.unicamp.br/ (Interessados nos licenciamento das tecnologias ou desenvolvimento de novas relacionadas ao tema).


Financiamento

Instituto Nacional de C,T&I em Materiais Complexos Funcionais (Inomat), CNPq/MCTI/Fapesp

Rede Nacional de Nanotoxicologia, CNPq/MCTI

Laboratório de Síntese de Nanoestruturas e Interação com Biossistemas (NanoBioss), SisNano/CNPq/MCTIC


Observação: Existem outras informações sobre Nanopartículas de Prata no Dossier Óxido de Grafeno e Derivados no LQES. Para acessar siga o link: http://www.lqes.iqm.unicamp.br/canal_cientifico/lqes_news/lqes_news_cit/.